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Acromegaly

An expert's perspective

Lewis S. Blevins, MD, professor of neurological surgery at UCSF and Director of the California Center for Pituitary Disorders, shares his knowledge and experience to promote better understanding of acromegaly and improve patient care. 

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Symptoms, care, and unmet needs in acromegaly

Symptoms

  • Enlarged hands or feet
  • Altered facial features
  • Joint pains
  • Muscle weakness and fatigue
  • Paresthesia (tingling or numbness in limbs)
  • Anxiety and depression
  • Headache
  • Soft tissue swellings
  • Excessive sweating
  • Sleep apnea

Diagnosis

Diagnosis is usually made by an endocrinologist or a pituitary specialist (neuroendocrinologist), although referral may be made by doctors from a range of medical specialties. In patients with symptoms of acromegaly, diagnosis includes the measurement of growth hormone levels and insulin growth factor 1 (IGF-1), and magnetic resonance imaging (MRI) to detect a tumor in the pituitary gland.

Management

Surgery and/or medical treatment. Radiotherapy may be considered when both surgery and medical therapy fail.

Explore more

Learn more about acromegaly. 

See acromegaly overview