Smart and versatile drug delivery
Camurus’ FluidCrystal technology is based on special combinations of endogenous polar lipids. When combined with active substances with clinically documented efficacy and safety profiles, it enables the development of new proprietary medicines both in a shorter time, and to a lower cost and risk compared to the development of new chemical substances.
with user-friendly administration
FluidCrystal injection depot is designed to provide treatment efficacy over extended periods – from days to months – with a single injection. It has the potential to reduce the burden of daily medication while increasing adherence to therapy.
The system’s simplicity, including a spontaneous self-association to a functional structure in the body, eliminates complicated manufacturing procedures and the need for mixing prior to administration. Medicines based on the FluidCrystal injection depot have the potential to be administered by the patients themselves or by healthcare professionals, without time-consuming and complicated reconstitution procedures. The long-acting release aims to reduce the patient’s burden of administering medication daily, improve the adherence to and results of the treatment, and improve the patient’s quality of life.
Mode of action
The FluidCrystal injection depot comprises a lipid-based liquid with a dissolved active ingredient that can easily be injected subcutaneously using a conventional syringe with a thin needle. Upon contact with fluids in the tissue, the lipid solution transforms into a liquid crystalline gel, which effectively encapsulates the active ingredient. The medicinal compound is slowly released as the liquid crystalline matrix gradually degrades in the tissue and the release can be controlled from several days to weeks or months depending on the composition. FluidCrystal is suitable for biological peptides as well as small molecules.
- Easy and convenient administration
- High treatment adherence
- Adapted to prefilled syringes and autoinjectors
- Long-acting release of active pharmaceutical ingredient
- Small injection volume with a thin needle
- Manufacturing by standard processes
- Suitable for peptides as well as small molecules